BDBM712848 US20250019371, Compound 32

SMILES CC(C)(Oc1cccc(N2CCC[C@@H](C(=O)N(Cc3ccc(-c4cccs4)cc3)C3CC3)C2)c1)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=NWWAOVBKNDIRFQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712848   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM712848(US20250019371, Compound 32)
Affinity DataIC50: 3.00E+4nMAssay Description:The β-catenin/BCL9 protein-protein interaction (PPI) has emerged as a potential therapeutic target to suppress the hyperactive Wnt/β-catenin signalin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM712848(US20250019371, Compound 32)
Affinity DataKi: <3.00E+4nMAssay Description:The β-catenin/BCL9 protein-protein interaction (PPI) has emerged as a potential therapeutic target to suppress the hyperactive Wnt/β-catenin signalin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent