BDBM712326 US20250011329, Compound III-35

SMILES COC(=O)COc1cc(F)c(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@H](O)C(F)F)C3)cn2)cc1F

InChI Key InChIKey=XVBUVZAYTMVGBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712326   

TargetHistone-lysine N-methyltransferase NSD2(Human)
K36 Therapeutics

US Patent
LigandPNGBDBM712326(US20250011329, Compound III-35)
Affinity DataIC50: 2nMAssay Description:A reaction mixture was prepared by adding oligonucleosomes from Chicken (0.05 mg/ml) to freshly prepared reaction buffer containing 50 mM Tris-HCl (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
K36 Therapeutics

US Patent
LigandPNGBDBM712326(US20250011329, Compound III-35)
Affinity DataIC50: 1nMAssay Description:A reaction mixture was prepared by adding oligonucleosomes from Chicken (0.05 mg/ml) to freshly prepared reaction buffer containing 50 mM Tris-HCl (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
Go to US Patent