BDBM712314 1-{4-[1-(3,4-dimethylphenyl)-1H- pyrazolo[4,3-c]quinolin-3-yl]phenyl}- 4-methylpiperazine::US20250011319, Compound 1.21

SMILES CC1C=CC(N2N=C(c3ccc(N4CCN(C)CC4)cc3)C3C=NC4C=CC=CC4C32)=CC1C

InChI Key InChIKey=UBJSVSLDSFCMTP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712314   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Lomond Therapeutics

US Patent
LigandPNGBDBM712314(1-{4-[1-(3,4-dimethylphenyl)-1H- pyrazolo[4,3-c]qu...)
Affinity DataKi: >50nMAssay Description:Table A: Primary Assay used to determine potency of HPK1 enzymatic activity inhibition. Compound activity was determined using recombinant HPK1 prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
Go to US Patent