BDBM712313 N-[3-(dimethylamino)propyl]-4-[1- (3,4-dimethylphenyl)-8-methoxy-1H- pyrazolo[4,3-c]quinolin-3-yl]-N- methylaniline::US20250011319, Compound 1.18

SMILES COC1=CC2c3c(c(-c4cccc(OC)c4)nn3C3C=C(N4CCN(C)CC4)C=CC3C)C=NC2C=C1

InChI Key InChIKey=NQZCGRJSFHJYKG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712313   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Lomond Therapeutics

US Patent
LigandPNGBDBM712313(N-[3-(dimethylamino)propyl]-4-[1- (3,4-dimethylphe...)
Affinity DataKi:  35nMAssay Description:Table A: Primary Assay used to determine potency of HPK1 enzymatic activity inhibition. Compound activity was determined using recombinant HPK1 prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
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