BDBM71175 (2-anilinoquinazolin-4-yl)-(2-furfuryl)amine;hydrochloride::4-N-(furan-2-ylmethyl)-2-N-phenylquinazoline-2,4-diamine;hydrochloride::MLS000767881::N*4*-Furan-2-ylmethyl-N*2*-phenyl-quinazoline-2,4-diamine::N4-(2-furanylmethyl)-N2-phenylquinazoline-2,4-diamine;hydrochloride::N4-(furan-2-ylmethyl)-N2-phenyl-quinazoline-2,4-diamine;hydrochloride::SMR000431203::cid_16240066

SMILES C(Nc1nc(Nc2ccccc2)nc2ccccc12)c1ccco1

InChI Key InChIKey=JBNQXHYEUTXOCA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 71175   

TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM71175(MLS000767881 | N4-(furan-2-ylmethyl)-N2-phenyl-qui...)
Affinity DataIC50: 2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetSon of sevenless homolog 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM71175(MLS000767881 | N4-(furan-2-ylmethyl)-N2-phenyl-qui...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed