BDBM711446 ((2-(2'-chloro-3'-(5-(((2- hydroxyethyl)amino)methyl)picolinamido)- 2-methyl-[1,1'-biphenyl]-3-yl)-6- (difluoromethoxy)benzo[d]oxazol-5- yl)methyl)-L-proline::US12187713, Example 302

SMILES Cc1c(-c2nc3cc(CN4CCCC4C(=O)O)c(OC(F)F)cc3o2)cccc1-c1cccc(NC(=O)c2ccc(CNCCO)cn2)c1Cl

InChI Key InChIKey=JEERLDBGFXYBHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711446   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM711446(((2-(2'-chloro-3'-(5-(((2- hydroxyethyl)amino)meth...)
Affinity DataIC50: 0.290nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent