BDBM711321 ((2-(3'-((3-(azetidin-1-ylmethyl)- 1,7-naphthyridin-8-yl)amino)-2,2'- dimethyl-[1,1'-biphenyl]-3-yl)-6- (difluoromethoxy)benzo[d]oxazol- 5-yl)methyl)proline::US12187713, Example 177

SMILES Cc1c(Nc2nccc3cc(CN4CCC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CCCC4C(=O)O)c(OC(F)F)cc3o2)c1C

InChI Key InChIKey=PPOKXRMQDHWDCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711321   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM711321(((2-(3'-((3-(azetidin-1-ylmethyl)- 1,7-naphthyridi...)
Affinity DataIC50: 0.940nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent