BDBM711216 ((2-(3'-(5-(((1s,4s)-7- azabicyclo[2.2.1] heptan-7-yl)methyl)-6- (difluoromethoxy) benzo[d]oxazol-2-yl)- 2,2'-dimethyl-[1,1'- biphenyl]-3-yl)-6- (difluoromethoxy) benzo[d]oxazol-5- yl)methyl)-L-proline::US12187713, Example 72

SMILES Cc1c(-c2nc3cc(CN4CCC[C@H]4C(=O)O)c(OC(F)F)cc3o2)cccc1-c1cccc(-c2nc3cc(CN4[C@H]5CC[C@@H]4CC5)c(OC(F)F)cc3o2)c1C

InChI Key InChIKey=RFOINCYITLNFEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 711216   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM711216(((2-(3'-(5-(((1s,4s)-7- azabicyclo[2.2.1] heptan-7...)
Affinity DataIC50: 0.980nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent