BDBM710540 Synthesis of (1R,2S,5S)—N-{(1S)-1-cyano-2-[(3S)-2-oxo(6,6-2H2)piperidin-3-yl]ethyl}-3-[N-(difluoroacetyl)-3-methyl-L-valyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide::US12186309, Compound 24

SMILES [2H]C1([2H])CC[C@@H](C[C@@H](C#N)NC(=O)[C@@H]2[C@@H]3[C@H](CN2C(=O)[C@@H](NC(=O)C(F)F)C(C)(C)C)C3(C)C)C(=O)N1

InChI Key InChIKey=SAGCWYXFUIQBSK-MGVXTIMCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710540   

TargetReplicase polyprotein 1a(2019-nCoV)
University of Alberta

US Patent
LigandPNGBDBM710540(Synthesis of (1R,2S,5S)—N-{(1S)-1-cyano-2-[(3S)-2-...)
Affinity DataIC50: 100nMAssay Description:A synthesized fluorescent substrate containing the cleavage site (indicated by the arrow, ↓) of SARS-CoV-2 3CLP (2-Abz-SVTLQ↓SG-Tyr(NO2)—R—NH2) was u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
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