BDBM710535 Synthesis of (2S)—N-{(1S)-1-cyano-2-[(3S)-2-oxopiperidin-3-yl]ethyl}-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanamide, 1::US12186309, Compound 1

SMILES CC(C)C[C@@H](C(=O)N[C@H](C#N)C[C@@H]1CCCNC1=O)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=XOFLGZWALVGNFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 710535   

TargetReplicase polyprotein 1a(2019-nCoV)
University of Alberta

US Patent
LigandPNGBDBM710535(Synthesis of (2S)—N-{(1S)-1-cyano-2-[(3S)-2-oxopip...)
Affinity DataIC50: 8.50E+3nMAssay Description:A synthesized fluorescent substrate containing the cleavage site (indicated by the arrow, ↓) of SARS-CoV-2 3CLP (2-Abz-SVTLQ↓SG-Tyr(NO2)—R—NH2) was u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
Go to US Patent