BDBM710478 1-[(3-cyanophenyl)- dideuteriomethyl]-3-[3- (trifluoromethyl)-1- bicyclo[1.1.1]pentanyl]urea::US20250002452, Example 52

SMILES [2H]C([2H])(NC(=O)NC12CC(C(F)(F)F)(C1)C2)c1cccc(C#N)c1

InChI Key InChIKey=AHCUICYGPXBJHO-NCYHJHSESA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710478   

LigandPNGBDBM710478(1-[(3-cyanophenyl)- dideuteriomethyl]-3-[3- (trifl...)
Affinity DataEC50:  240nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

LigandPNGBDBM710478(1-[(3-cyanophenyl)- dideuteriomethyl]-3-[3- (trifl...)
Affinity DataEC50:  240nMAssay Description:Solutions were of the following composition:Earle's balanced salt solution (in mM): 135 NaCl, 5.4 KCl, 5 Glucose, 2 CaCl2), 1 MgCl2, 5 HEPES, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent