BDBM710395 US20250000854, Example 4

SMILES Cc1cc(-c2c(-c3ccc4c(=O)[nH]cc(CN)c4c3)cnn2C)c(C#N)c2ccccc12

InChI Key InChIKey=AKIXNJFKWKNNMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710395   

LigandPNGBDBM710395(US20250000854, Example 4)
Affinity DataIC50: 2.70nMAssay Description:The assay was carried out in 384-well low volume black plates in a reaction mixture containing 10 nM PRMT5/MEP50 complex, biotinylated histone H4 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

LigandPNGBDBM710395(US20250000854, Example 4)
Affinity DataIC50: 29nMAssay Description:MTA is excluded.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent