BDBM710394 US20250000854, Example 3

SMILES Cn1ncc(-c2ccc3c(=O)[nH]cc(CN)c3c2)c1-c1c(F)c(Cl)cc(OC2CC2)c1C#N

InChI Key InChIKey=UTESOWDSXZVOAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710394   

LigandPNGBDBM710394(US20250000854, Example 3)
Affinity DataIC50: 7.60nMAssay Description:The assay was carried out in 384-well low volume black plates in a reaction mixture containing 10 nM PRMT5/MEP50 complex, biotinylated histone H4 pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

LigandPNGBDBM710394(US20250000854, Example 3)
Affinity DataIC50: 68nMAssay Description:MTA is excluded.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent