BDBM709825 6-(5'-(3,5-difluorophenyl)- 3'-oxotetrahydro-3'H- spiro[piperidine-4,2'- pyrrolo[2,1-b]thiazol]-1- yl)pyrimidine-4- carbonitrile::US12180226, Example 4.111

SMILES N#Cc1cc(N2CCC3(CC2)SC2CCC(c4cc(F)cc(F)c4)N2C3=O)ncn1

InChI Key InChIKey=FFSPPUCWAHNXTB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709825   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709825(6-(5'-(3,5-difluorophenyl)- 3'-oxotetrahydro-3'H- ...)
Affinity DataEC50:  3.81E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
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