BDBM709705 (5'S,7a'R)-1- (benzenecarbonyl)-3- fluoro-5'-(5-fluoro-6- methylpyridin-3- yl)tetrahydro-3'H- spiro[piperidine-4,2'- pyrrolo[2,1-b][1,3]oxazol]- 3'-one::US12180226, Example 2.9

SMILES Cc1ncc([C@@H]2CC[C@H]3OC4(CCN(C(=O)c5ccccc5)CC4F)C(=O)N32)cc1F

InChI Key InChIKey=RIUCQBTUQNWAQJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709705   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709705((5'S,7a'R)-1- (benzenecarbonyl)-3- fluoro-5'-(5-fl...)
Affinity DataEC50:  1.06E+5nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
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