BDBM709702 (5'S,7a'R)-1-benzoyl-5'-(4- fluorophenyl)tetrahydro- 3'H-spiro[piperidine-4,2'- pyrrolo[2,1-b]oxazol]-3'- one::US12180226, Example 2.8

SMILES O=C(c1ccccc1)N1CCC2(CC1)O[C@@H]1CC[C@@H](c3ccc(F)cc3)N1C2=O

InChI Key InChIKey=LHRGNLJWJHGPQL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709702   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709702((5'S,7a'R)-1-benzoyl-5'-(4- fluorophenyl)tetrahydr...)
Affinity DataEC50:  3.68E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent