BDBM709694 (5'S,7a'R)-1-benzoyl-5'-(5- fluoro-6-methylpyridin-3- yl)tetrahydro-3'H- spiro[piperidine-4,2'- pyrrolo[2,1-b]oxazol]-3'- one, TFA salt.::US12180226, Example 2.1

SMILES Cc1ncc([C@@H]2CC[C@H]3OC4(CN(C(=O)c5ccccc5)C4)C(=O)N32)cc1F

InChI Key InChIKey=LTVVSHUINZAVRS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709694   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709694((5'S,7a'R)-1-benzoyl-5'-(5- fluoro-6-methylpyridin...)
Affinity DataEC50:  7.65E+4nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent