BDBM709668 US12180226, Example 1.2::methyl (5'S,7a'R)-5'-(3,5- difluorophenyl)-3'- oxotetrahydro-1H,3'H- spiro[piperidine-4,2'- pyrrolo[2,1-b] [1,3]oxazole]-1- carboxylate

SMILES COC(=O)N1CCC2(CC1)O[C@@H]1CC[C@@H](c3cc(F)cc(F)c3)N1C2=O

InChI Key InChIKey=SQSWETDHMMJGDH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709668   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709668(methyl (5'S,7a'R)-5'-(3,5- difluorophenyl)-3'- oxo...)
Affinity DataEC50:  1.15E+5nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
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