BDBM709656 N-(3-(4-(4-(3- cyano-4- methoxypyrazolo[1, 5-a]pyridin-6-yl)- 1H-pyrazol-1- yl)piperidine-1- carbonyl)phenyl)eth- enesulfonamide::US12180207, Example 188
SMILES C=CS(=O)(=O)Nc1cccc(C(=O)N2CCC(N/C=C(C=N)c3cc(OC)c4c(C#N)cnn4c3)CC2)c1
InChI Key InChIKey=JEBDREWJGILFIZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709656
Affinity DataIC50: 14nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair