BDBM709616 (E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)azetidin-3- yl)methyl)piperidin- 4-yl)-1H-pyrazol- 4-yl)-4-methoxypyrazolo [1,5-a]pyridine-3-carbonitrile::US12180207, Example 146
SMILES COc1cc(-c2cnn(C3CCN(CC4CN(C(=O)/C=C/CN(C)C)C4)CC3)c2)cn2ncc(C#N)c12
InChI Key InChIKey=KEKXLNDHFOMLPS-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709616
Affinity DataIC50: 51nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair