BDBM709602 6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidin-4-yl)- 1H-pyrazol-4-yl)-4-(2- fluorophenyl)pyrazolo[1,5- a]pyridine-3- carbonitrile::US12180207, Example 131

SMILES C=CC(=O)N1CC(C(=O)N2CCC(n3cc(-c4cc(-c5ccccc5F)c5c(C#N)cnn5c4)cn3)CC2)C1

InChI Key InChIKey=ZWHKWOQATUSJSR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 709602   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709602(6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidi...)
Affinity DataIC50: 7nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709602(6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidi...)
Affinity DataIC50: 1nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709602(6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidi...)
Affinity DataIC50: 9nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM709602(6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidi...)
Affinity DataIC50: 10nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709602(6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidi...)
Affinity DataIC50: 4nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent