BDBM709601 N-(4-(6-(1-(1-(1- acryloylazetidine-3- carbonyl)piperidin-4-yl)- 1H-pyrazol-4-yl)-3- cyanopyrazolo[1,5- a]pyridin-4-yl)-3- fluorophenyl)cyclopropane- carboxamide::US12180207, Example 130
SMILES C=CC(=O)N1CC(C(=O)N2CCC(n3cc(-c4cc(-c5ccc(NC(=O)C6CC6)cc5F)c5c(C#N)cnn5c4)cn3)CC2)C1
InChI Key InChIKey=IGXJTXDPMDXZJZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709601
Affinity DataIC50: 7nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair