BDBM709571 6-(4-(4-(1- acryloylazetidine-3- carbonyl)piperazin-1- yl)phenyl)-4- methoxypyrazolo[1,5- a]pyridine-3-carbonitrile::US12180207, Example 100
SMILES C=CC(=O)N1CC(C(=O)N2CCN(c3ccc(-c4cc(OC)c5c(C#N)cnn5c4)cc3)CC2)C1
InChI Key InChIKey=JEDTURAIMNGEAI-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709571
Affinity DataIC50: 57nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair