BDBM709505 N-((1R,3R)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,5- a]pyridin-6-yl)-1H- pyrazol-1-yl)piperidine-1- carbonyl)cyclopentyl)acryl- amide::US12180207, Example 34

SMILES C=CC(=O)N[C@@H]1CC[C@@H](C(=O)N2CCC(n3cc(-c4cc(OC)c5c(C#N)cnn5c4)cn3)CC2)C1

InChI Key InChIKey=QTQBJRCBSLLTBA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 709505   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709505(N-((1R,3R)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 231nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709505(N-((1R,3R)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 36nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709505(N-((1R,3R)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 19nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM709505(N-((1R,3R)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 5nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709505(N-((1R,3R)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 2nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent