BDBM709502 6-(1-(1-(1-acryloyl-3- cyanopyrrolidine-3- carbonyl)piperidin-4-yl)- 1H-pyrazol-4-yl)-4- methoxypyrazolo[1,5- a]pyridine-3-carbonitrile::US12180207, Example 31
SMILES N#CC1(C(=O)N2CCC(n3cc(-c4cc(OC)c5c(C#N)cnn5c4)cn3)CC2)CCN(C(=O)C=C)C1
InChI Key InChIKey=CYOSEXIUDLKBBP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709502
Affinity DataIC50: 26nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair