BDBM709474 6-(1-(1-(9-acryloyl-3-oxa- 7,9- diazabicyclo[3.3.1]nonane- 7-carbonyl)piperidin-4- yl)-1H-pyrazol-4-yl)-4- methoxypyrazolo[1,5- a]pyridine-3-carbonitrile::US12180207, Example 3
SMILES C=CC(=O)N1C2COCC1CN(C(=O)N1CCC(n3cc(-c4cc(OC)c5c(C#N)cnn5c4)cn3)CC1)C2
InChI Key InChIKey=KPDFFUWYNAEXCW-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 709474
Affinity DataIC50: 44nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:he potency of compounds inhibiting human isoforms of FGFR kinase was determined using Life Technologies' Homogeneous Time Resolved Fluorescence (...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:FGFR1 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:FGFR2 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:FGFR3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphorylation b...More data for this Ligand-Target Pair