BDBM709400 WO2018/027892, Example 2

SMILES NC/C(=CF)COc1cnc(N2CCC(O)CC2)nc1

InChI Key InChIKey=LFMFZMBGSUKTCO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 709400   

TargetAmine oxidase [copper-containing] 3(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM709400(WO2018/027892, Example 2)
Affinity DataIC50: 20nMAssay Description:For the determination of AOC3 activity or compound inhibition potency, the compound inhibitors are dissolved in DMSO and adjusted to the respective a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
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TargetAmine oxidase [copper-containing] 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM709400(WO2018/027892, Example 2)
Affinity DataIC50: 1.09E+3nMAssay Description:An AOC2 enzyme containing cell homogenate is generated by transient transfection of 6×106 HEK293 cells per flask (T75) with 9 μg pCMV-SPORT6-AOC2 (BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetDiamine oxidase [copper-containing](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM709400(WO2018/027892, Example 2)
Affinity DataIC50: 269nMAssay Description:For the determination of AOC1 activity or compound AOC1 inhibition potency, the compound inhibitors are dissolved in DMSO and adjusted to the respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent