BDBM709377 US12178809, Example 52

SMILES COC(=O)[C@H]1[C@@H]2CN(S(=O)(=O)c3ccc(OC/C(=C/F)CN)nc3)C[C@@H]21

InChI Key InChIKey=DJLKGNHSKWNRRO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 709377   

TargetAmine oxidase [copper-containing] 3(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM709377(US12178809, Example 52)
Affinity DataIC50: 9nMAssay Description:For the determination of AOC3 activity or compound inhibition potency, the compound inhibitors are dissolved in DMSO and adjusted to the respective a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
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TargetAmine oxidase [copper-containing] 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM709377(US12178809, Example 52)
Affinity DataIC50: 315nMAssay Description:An AOC2 enzyme containing cell homogenate is generated by transient transfection of 6×106 HEK293 cells per flask (T75) with 9 μg pCMV-SPORT6-AOC2 (BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetDiamine oxidase [copper-containing](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM709377(US12178809, Example 52)
Affinity DataIC50: 4.18E+4nMAssay Description:For the determination of AOC1 activity or compound AOC1 inhibition potency, the compound inhibitors are dissolved in DMSO and adjusted to the respect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent