BDBM709320 (Z)-3-fluoro-4-(2-methylpyridin-3- ylsulfonyl)but-2-en-1-amine::US12178791, Compound 47

SMILES Cc1ncccc1S(=O)(=O)C/C(F)=C/CN

InChI Key InChIKey=MPNBOZVAFXFVHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 709320   

TargetProtein-lysine 6-oxidase(Bovine)
Syntara

US Patent
LigandPNGBDBM709320((Z)-3-fluoro-4-(2-methylpyridin-3- ylsulfonyl)but-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Syntara

US Patent
LigandPNGBDBM709320((Z)-3-fluoro-4-(2-methylpyridin-3- ylsulfonyl)but-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent