BDBM709319 (Z)-3-fluoro-4-(6-methylpyridin-3- ylsulfonyl)but-2-en-1-amine::US12178791, Compound 46

SMILES Cc1ccc(S(=O)(=O)C/C(F)=C/CN)cn1

InChI Key InChIKey=BRXROODHZFSLIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 709319   

TargetProtein-lysine 6-oxidase(Bovine)
Syntara

US Patent
LigandPNGBDBM709319((Z)-3-fluoro-4-(6-methylpyridin-3- ylsulfonyl)but-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Syntara

US Patent
LigandPNGBDBM709319((Z)-3-fluoro-4-(6-methylpyridin-3- ylsulfonyl)but-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent