BDBM709318 (Z)-3-fluoro-4-(2-isopropylpyridin-3- ylsulfonyl)but-2-en-1-amine::US12178791, Compound 45

SMILES CC(C)c1ncccc1S(=O)(=O)C/C(F)=C/CN

InChI Key InChIKey=GSEOYCBTMMCEKX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 709318   

TargetProtein-lysine 6-oxidase(Bovine)
Syntara

US Patent
LigandPNGBDBM709318((Z)-3-fluoro-4-(2-isopropylpyridin-3- ylsulfonyl)b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Syntara

US Patent
LigandPNGBDBM709318((Z)-3-fluoro-4-(2-isopropylpyridin-3- ylsulfonyl)b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetAmine oxidase [copper-containing] 3 [34-763](Human)
Syntara

US Patent
LigandPNGBDBM709318((Z)-3-fluoro-4-(2-isopropylpyridin-3- ylsulfonyl)b...)
Affinity DataIC50: 3.00E+4nMAssay Description:Briefly, a cloned cDNA template corresponding to residues 34-763 of human SSAO/VAP-1, and incorporating a mouse Ig kappa (κ) signal sequence, N-termi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent