BDBM709290 (Z)-3-(3-(4-amino-2-fluorobut-2- enylsulfonyl)phenoxy)-N,N- dimethylbenzenesulfonamide::US12178791, Compound 17

SMILES CN(C)S(=O)(=O)c1cccc(Oc2cccc(S(=O)(=O)C/C(F)=C/CN)c2)c1

InChI Key InChIKey=XPDDTRMHIYSLIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 709290   

TargetProtein-lysine 6-oxidase(Bovine)
Syntara

US Patent
LigandPNGBDBM709290((Z)-3-(3-(4-amino-2-fluorobut-2- enylsulfonyl)phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Syntara

US Patent
LigandPNGBDBM709290((Z)-3-(3-(4-amino-2-fluorobut-2- enylsulfonyl)phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent