BDBM709066 6-(5-{[(1R)-1-[2-fluoro-5-(tri-fluoromethyl)phenyl]ethyl]-carbamoyl}-6-(deutero)meth-oxypyridin-3-yl)-N-methyl-1H-indazole-3-carboxamide::US12172975, Example 31

SMILES [2H]C([2H])([2H])Oc1ncc(-c2ccc3c(C(=O)NC)n[nH]c3c2)cc1C(=O)N[C@H](C)c1cc(C(F)(F)F)ccc1F

InChI Key InChIKey=LGHULZYQMDJDRH-HPRDVNIFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709066   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM709066(6-(5-{[(1R)-1-[2-fluoro-5-(tri-fluoromethyl)phenyl...)
Affinity DataIC50: 2.30nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1 (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
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