BDBM709056 (S)-7'-(3,5- difluorophenyl)-1- (phenylsulfonyl) dihydro-l'H,3'H,5'H- spiro[piperidine-4,2'- pyrazolo[1,2- a]pyrazol]-l'-one::US20240425524, Example 5.3

SMILES O=C1N2[C@H](c3cc(F)cc(F)c3)CCN2CC12CCN(S(=O)(=O)c1ccccc1)CC2

InChI Key InChIKey=HMKQSJGTYDKKMV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 709056   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM709056((S)-7'-(3,5- difluorophenyl)-1- (phenylsulfonyl) d...)
Affinity DataEC50:  830nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution: top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
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