BDBM708725 US20240425497, Example 53

SMILES N#Cc1c(CO)[nH]c2c(=O)n(-c3cc(-c4ccc(F)cc4C(=O)N4CC(F)C4)cc(C4CC4)n3)cc(C(F)(F)F)c12

InChI Key InChIKey=KRXGJJKKQXXHMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708725   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM708725(US20240425497, Example 53)
Affinity DataIC50: 100nMAssay Description:The assays were performed in assay buffer consisting of 20 mM Hepes, 150 mM NaCl, 0.01% Triton X-100, 0.5 mM TCEP, 0.01% BSA. On the day of the assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent