BDBM708709 US20240425497, Example 37

SMILES O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cnc3cc(CN4CC5CCC4C5)[nH]c3c2=O)n1)N1CC(F)C1

InChI Key InChIKey=JXJWLRATYWQHJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 708709   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM708709(US20240425497, Example 37)
Affinity DataIC50: 100nMAssay Description:The assays were performed in assay buffer consisting of 20 mM Hepes, 150 mM NaCl, 0.01% Triton X-100, 0.5 mM TCEP, 0.01% BSA. On the day of the assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent