BDBM708564 (S)-3-(1-(5-(2-oxa-6- azaspiro[3.3]heptan-6- yl)pyridin-3- yl)pyrrolidin-3-yl)-4- methyl-N-(3- (trifluoromethyl)phenyl) benzamide::US20240425482, Example 37

SMILES Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1[C@@H]1CCN(c2cncc(N3CC4(COC4)C3)c2)C1

InChI Key InChIKey=CIQWKFBQURLOAF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708564   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708564((S)-3-(1-(5-(2-oxa-6- azaspiro[3.3]heptan-6- yl)py...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708564((S)-3-(1-(5-(2-oxa-6- azaspiro[3.3]heptan-6- yl)py...)
Affinity DataKi:  17.5nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent