BDBM708540 4-methyl-3-(1-(5-(4- methylpiperazin-1- yl)pyridin-3- yl)pyrrolidin-3-yl)-N-(3- (trifluoromethyl)phenyl) benzamide::US20240425482, Example 12

SMILES Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C1CCN(c2cncc(N3CCN(C)CC3)c2)C1

InChI Key InChIKey=JWSBJQSDIDGJKH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708540   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708540(4-methyl-3-(1-(5-(4- methylpiperazin-1- yl)pyridin...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708540(4-methyl-3-(1-(5-(4- methylpiperazin-1- yl)pyridin...)
Affinity DataKi:  17.5nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent