BDBM708538 N-methyl-5-(3-(2- methyl-5-((3- (trifluoromethyl)phenyl) carbamoyl)phenyl)pyrrolidin- 1-yl)nicotinamide::US20240425482, Example 10

SMILES CNC(=O)c1cncc(N2CCC(c3cc(C(=O)Nc4cccc(C(F)(F)F)c4)ccc3C)C2)c1

InChI Key InChIKey=LWGGNTWUQKSVCY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708538   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708538(N-methyl-5-(3-(2- methyl-5-((3- (trifluoromethyl)p...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708538(N-methyl-5-(3-(2- methyl-5-((3- (trifluoromethyl)p...)
Affinity DataKi:  17.5nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent