BDBM708489 1-(3-fluorobenzofuran-5-yl)-N- methylpropan-2-amine::US20240425470, Compound 2

SMILES CNC(C)Cc1ccc2occ(F)c2c1

InChI Key InChIKey=JOMHNHGHKJLYGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 708489   

TargetSodium-dependent serotonin transporter(Human)
Atai Life Sciences

US Patent
LigandPNGBDBM708489(1-(3-fluorobenzofuran-5-yl)-N- methylpropan-2-amin...)
Affinity DataIC50: 5.72E+3nMAssay Description:Serotonin transporter (SERT) Uptake Inhibition: Compound activity was assessed using an in vitro assay. Briefly, HEK cells expressing recombinant SER...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Atai Life Sciences

US Patent
LigandPNGBDBM708489(1-(3-fluorobenzofuran-5-yl)-N- methylpropan-2-amin...)
Affinity DataIC50: 9.59E+3nMAssay Description:Compound activity was assessed using a convenient in vitro assay. Briefly, HEK cells expressing recombinant DAT were plated at 50,000 cells/well on a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Atai Life Sciences

US Patent
LigandPNGBDBM708489(1-(3-fluorobenzofuran-5-yl)-N- methylpropan-2-amin...)
Affinity DataIC50: 5.02E+3nMAssay Description:Compound activity was assessed using a convenient in vitro assay. Briefly, HEK cells expressing recombinant NET were plated at 50,000 cells/well on a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent