BDBM708488 1-(3-fluorobenzofuran-5- yl)propan-2-amine::US20240425470, Compound 1

SMILES CC(N)Cc1ccc2occ(F)c2c1

InChI Key InChIKey=JSJJCUHYSCBIBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 708488   

TargetSodium-dependent serotonin transporter(Human)
Atai Life Sciences

US Patent
LigandPNGBDBM708488(1-(3-fluorobenzofuran-5- yl)propan-2-amine | US202...)
Affinity DataIC50: 6.75E+3nMAssay Description:Serotonin transporter (SERT) Uptake Inhibition: Compound activity was assessed using an in vitro assay. Briefly, HEK cells expressing recombinant SER...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Atai Life Sciences

US Patent
LigandPNGBDBM708488(1-(3-fluorobenzofuran-5- yl)propan-2-amine | US202...)
Affinity DataIC50: 1.56E+4nMAssay Description:Compound activity was assessed using a convenient in vitro assay. Briefly, HEK cells expressing recombinant DAT were plated at 50,000 cells/well on a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Atai Life Sciences

US Patent
LigandPNGBDBM708488(1-(3-fluorobenzofuran-5- yl)propan-2-amine | US202...)
Affinity DataIC50: 4.73E+3nMAssay Description:Compound activity was assessed using a convenient in vitro assay. Briefly, HEK cells expressing recombinant NET were plated at 50,000 cells/well on a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent