BDBM708043 2-((1S,3R)-3-(3,4- dichlorobenzamido)cyclohexyl)-5- hydroxy-N-(isoxazol-4-yl)-1- methyl-6-oxo-1,6- dihydropyrimidine-4-carboxamide::US12172990, Example 82

SMILES Cn4c([C@H]2CCC[C@@H](NC(=O)c1ccc(Cl)c(Cl)c1)C2)nc(C(=O)Nc3cnoc3)c(O)c4=O

InChI Key InChIKey=YBULGAQHLGICPF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708043   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708043(2-((1S,3R)-3-(3,4- dichlorobenzamido)cyclohexyl)-5...)
Affinity DataIC50: 100nMAssay Description:Compound potency was assessed through a fluorescence assay measuring degradation of a custom dsDNA substrate possessing a fluorophore-quencher pair o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708043(2-((1S,3R)-3-(3,4- dichlorobenzamido)cyclohexyl)-5...)
Affinity DataIC50: 100nMAssay Description:Compound potency was assessed through a fluorescence assay measuring degradation of a custom dsDNA substrate possessing a fluorophore-quencher pair o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent