BDBM708030 5-hydroxy-2-(1- isonicotinoylpiperidin- 3-yl)-N-(isoxazol-4- yl)-1-methyl-6-oxo- 1,6- dihydropyrimidine-4- carboxamide::US12172990, Example 63

SMILES Cn1c(C2CCCN(C(=O)c3ccncc3)C2)nc(C(=O)Nc2cnoc2)c(O)c1=O

InChI Key InChIKey=CZQOYDOLOMZOJC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708030   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708030(5-hydroxy-2-(1- isonicotinoylpiperidin- 3-yl)-N-(i...)
Affinity DataIC50: 55nMAssay Description:Compound potency was assessed through a fluorescence assay measuring degradation of a custom dsDNA substrate possessing a fluorophore-quencher pair o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708030(5-hydroxy-2-(1- isonicotinoylpiperidin- 3-yl)-N-(i...)
Affinity DataIC50: 55nMAssay Description:Compound potency was assessed through a fluorescence assay measuring degradation of a custom dsDNA substrate possessing a fluorophore-quencher pair o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
US Patent