BDBM707669 US20240417387, Example 049

SMILES N[C@@H]1C[C@H](N)CN(CCCNC(=O)[C@H]2CC[C@H](C(F)(F)c3cc(Cl)nc(N4CCN(S(=O)(=O)c5ccc(N6C[C@H](N)CC6=O)cc5)CC4)c3)CC2)C1

InChI Key InChIKey=MRDKRYRGSQSXEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707669   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM707669(US20240417387, Example 049)
Affinity DataIC50: 7nMAssay Description:The inhibitory potency of compounds of Escherichia coli UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined in an enzymatic assay. UDP-2,3-diac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent