BDBM707651 US20240417387, Example 002

SMILES N[C@@H]6CC(=O)N(c5ccc(S(=O)(=O)N4CCN(c3cc(C(F)(F)[C@@H]2CC[C@@H](C(=O)NCC1CNC1)CC2)cc(Cl)n3)CC4)cc5)C6

InChI Key InChIKey=SNHCANXWSPQOBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707651   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM707651(US20240417387, Example 002)
Affinity DataIC50: 2nMAssay Description:The inhibitory potency of compounds of Escherichia coli UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined in an enzymatic assay. UDP-2,3-diac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent