BDBM707649 US20240417387, Example 001

SMILES NCC(O)CNC(=O)[C@H]1CC[C@H](C(F)(F)c2cc(Cl)nc(N3CCN(S(=O)(=O)c4ccc(N5C[C@H](N)CC5=O)cc4)CC3)c2)CC1

InChI Key InChIKey=ROHAELRTRDXOTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707649   

TargetUDP-2,3-diacylglucosamine hydrolase()
Hoffmann-La Roche

US Patent
LigandPNGBDBM707649(US20240417387, Example 001)
Affinity DataIC50: 2nMAssay Description:The inhibitory potency of compounds of Escherichia coli UDP-2,3-diacylglucosamine hydrolase (LpxH) was determined in an enzymatic assay. UDP-2,3-diac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/1/2025
Entry Details
Go to US Patent