BDBM707395 2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-5-chloro-6- (trifluoromethyl)-4-pyrimidinyl}- 1-pyrazolyl)-1-(1-piperazinyl)-1- ethanone::US20240409530, Compound A29

SMILES O=C(Cn1cc(-c2nc(N3CC[C@@H]3C(F)(F)F)nc(C(F)(F)F)c2Cl)cn1)N1CCNCC1

InChI Key InChIKey=MYDDGNXMHZLYMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707395   

TargetKetohexokinase(Human)
Centennial Therapeutics

US Patent
LigandPNGBDBM707395(2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-5-...)
Affinity DataIC50: 5.03nMAssay Description:Determination of Human and Rat recombinant KHK-A and KHK-C isozyme IC50 ValuesAn assay reagent cocktail was prepared by combining NADH, water, TEA, K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
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