BDBM707228 2 (1H)-one ::US20240400586, Compound 45

SMILES CCC1=Cc2ncc(CN3CCN(c4cn5cc(C(F)F)nc5cn4)CC3)cc2CC1=O

InChI Key InChIKey=AFZLLXUFLZGRGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707228   

TargetPoly [ADP-ribose] polymerase 1(Human)
Haisco Pharmaceutical Group

US Patent
LigandPNGBDBM707228(2 (1H)-one | US20240400586, Compound 45)
Affinity DataIC50: 0.730nMAssay Description:Table 1: PARP1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent