BDBM707209 N-(3,3-difluorocyclobutyl)-5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)picolinamide ::US20240400586, Compound 25

SMILES CCC1=CC2N=CC(CN3CCN(c4ccc(C(=O)NC5CC(F)(F)C5)nc4)CC3)CC2NC1=O

InChI Key InChIKey=PSMGAGLJARYDMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707209   

TargetPoly [ADP-ribose] polymerase 1(Human)
Haisco Pharmaceutical Group

US Patent
LigandPNGBDBM707209(N-(3,3-difluorocyclobutyl)-5-(4-((7-ethyl-6-oxo-5,...)
Affinity DataIC50: 0.880nMAssay Description:Table 1: PARP1 chemical fluorescence detection kit was purchased from BPS Bioscience. The histone solution in the kit was diluted 5× with 1×PBS, and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
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