BDBM707185 US20240400582, Compound Example 1

SMILES C[C@@H]1COC2NC=NC=C2c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc3nc(C(F)F)n1c23

InChI Key InChIKey=IRJUOLZMONEIKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 707185   

TargetTyrosine-protein kinase ABL1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM707185(US20240400582, Compound Example 1)
Affinity DataIC50: 0.430nMAssay Description:Capillary electrophoresis was used to detect the phosphorylation conversion rate of the substrate peptide to determine the IC50 value of the test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent